Anorganic bovine bone (Bio-Oss®) has been extensively used for reconstruction of posterior area ofmaxilla in sinus lift procedure; however, a new graft material (Lumina-Bone Porous®), that has a differentmanufacturing process, has not been yet compared in clinical and histological terms. The manufacturing process ofbovine bone graft is related to size and porosity of the particles, and this can change osteoconductive property ofthe material and bone formation. The use of Lumina-Porus® could improve bone formation, reduce the remainingparticles of the biomaterial using a low-cost material. The aim of this research was to compare the clinical,radiological, and histomorphometrical results from maxillary sinus lift with two different anorganic bovine bonesubstitutes Bio-Oss® (control) and Lumina-Bone Porous® (test).